This article provides a general overview of the interface between law and telemedicine. The piece is not a roadmap for any one legal system but rather attempts to illustrate issues which cut across borders, recognizing that each country's legal system may have unique impacts on telemedicine. The article notes that the nature of the legal issue will be colored by the nature of the telemedicine application in question, as well as by consideration of whether a given program is in a development or applied phase. Broad topics to be considered in this piece include medical liability, patient rights, privacy and licensure.